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Genitourinary Pathology: Diagnosis and Treatment of Urologic and Reproductive Diseases



We evaluate genitourinary disorders resulting in chronic kidney disease (CKD). Examples of such disorders include chronic glomerulonephritis, hypertensive nephropathy, diabetic nephropathy, chronic obstructive uropathy, and hereditary nephropathies. We also evaluate nephrotic syndrome due to glomerular dysfunction under these listings.




genitourinary



The Genitourinary Steering Committee (GUSC) was established in 2008. At monthly meetings, the GUSC addresses the design, prioritization, and evaluation of concepts for phase 2 and phase 3 clinical trials in genitourinary cancers. View the GUSC member roster.


We take a team approach to treating genitourinary cancers, and you are an important part of the team. Specialized medical oncologists, surgeons and radiation oncologists collaborate closely to customize your cancer treatment.


Disorders of the genitourinary system in children are often detected by fetal ultrasound prior to birth. If not detected on fetal ultrasound, often children will develop a urinary tract infection that will prompt your child's doctor to perform special diagnostic tests that may detect an abnormality. Some diseases of the kidney do not reveal themselves until later in life or after a child has a bacterial infection or an immune disorder.


All humans are colonized with Candida species, mostly Candida albicans, yet some develop diseases due to Candida, among which genitourinary manifestations are extremely common. The forms of genitourinary candidiasis are distinct from each other and affect different populations. While vulvovaginal candidiasis affects mostly healthy women, candiduria occurs typically in elderly, hospitalized, or immunocompromised patients and in neonates. Despite its high incidence and clinical relevance, genitourinary candidiasis is understudied, and therefore, important questions about pathogenesis and treatment guidelines remain to be resolved. In this review, we summarize the current knowledge about genitourinary candidiasis.


The genitourinary system is also known as the urogenital system and is comprised of the reproductive and urinary organs which includes the kidneys, bladder, prostate, testes and penis. Kidney and bladder cancers are discussed in another section, so this article will focus on the the male genital system.


Symptoms vary and are determined by the area where the disease develops. However, the existence of any of these symptoms does not necessarily signify genitourinary cancer, but a doctor should always be consulted for a correct diagnosis. If it is genitourinary cancer and symptoms are ignored, it could progress to an advanced stage and less easily treated. The most common symptoms for this genitourinary cancer type are:


Moffitt Cancer Center's Genitourinary Oncology Program is a world-class destination for patients with cancers of the urinary tract and male genital organs. We are a high-volume, National Cancer Institute-designated Comprehensive Cancer Center with concentrated programs for even the rarest malignancies, and many of our physicians are fellowship-trained in urologic sub-specialties. As a result, we are a trusted partner of physicians across the nation who need to refer their patients to an advanced program for genitourinary cancer diagnosis or treatment.


For many women, vaginal atrophy not only makes intercourse painful but also leads to distressing urinary symptoms. Because the condition causes both vaginal and urinary symptoms, doctors use the term "genitourinary syndrome of menopause (GSM)" to describe vaginal atrophy and its accompanying symptoms.


Regular sexual activity, either with or without a partner, may help prevent genitourinary syndrome of menopause. Sexual activity increases blood flow to your vagina, which helps keep vaginal tissues healthy.


Obstructive genitourinary defects are congenital narrowing or absence of urinary tract structures. These conditions are the most common congenital defect of any organ system. The severity of the problems for the child depends on the degree and level of the obstruction. For example, the most common type of obstruction is at the uteropelvic junction (UPJ), an obstruction that occurs between the ureter and the kidney at the place they join. Due to this obstruction urine does not easily pass through the ureter and consequently it backs up through the renal system. The second most common obstruction is where the ureter enters the back wall of the bladder, the ureterovesicular junction (UVJ). UVJ obstruction, which usually involves only one kidney, will result in backflow and enlargement of the ureter (called megaureter).


Any type of urinary tract obstruction will interfere with normal fetal development, and the degree of damage depends on the severity of the obstruction. The spectrum of fetal injury depends on the type, degree and duration of the obstruction. In unborn babies with high-grade obstruction, urine output is decreased, leading to lack of amniotic fluid (called oligohydramnios). The lungs also will not develop properly due to the lack of amniotic fluid. Hydronephrosis, which is kidney damage, is a frequent result of an obstruction in the urinary system. Our program has been tracking obstructive genitourinary defect (renal pelvis and ureter only) among live births in select counties since 2005 and are gradually expanding statewide.


Abnormalities of the genitourinary system are among themost common fetal structural malformations. Such anomalies range from mild (eg, mild urinary tract dilation) to severelife-threatening anomalies (eg, bilateral renal agenesis).


Genitourinary cancers can have a profound effect on your life, whether your disease is in the prostate, kidney, bladder, adrenal glands, penis or testicles. Experts at MUSC Hollings Cancer Center are pioneering treatments to fight genitourinary cancers, giving you access to the very latest techniques and therapies.


At Hollings, our team of prostate and genitourinary cancer specialists is dedicated to giving you the most accurate and effective treatment possible. Thanks to breakthroughs in cancer medicine, we are able to offer you a variety of treatments including:


  • processing.... Drugs & Diseases > Infectious Diseases Chlamydia (Chlamydial Genitourinary Infections) Updated: Mar 09, 2021 Author: Shahab Qureshi, MD, FACP; Chief Editor: Michael Stuart Bronze, MD more...

  • Share Email Print Feedback Close Facebook Twitter LinkedIn WhatsApp webmd.ads2.defineAd(id: 'ads-pos-421-sfp',pos: 421); Sections Chlamydia (Chlamydial Genitourinary Infections) Sections Chlamydia (Chlamydial Genitourinary Infections) Overview Background

  • Pathophysiology Etiology Epidemiology Prognosis Patient Education Show All Presentation History

  • Physical Examination Complications Show All DDx Workup Approach Considerations

  • Basic Laboratory Studies Cytology and Cell Culture Molecular Techniques for Detecting Antigen, DNA, or RNA/Rapid Tests Nucleic Acid Amplification Tests Serology CT, Radiography, and Ultrasonography Screening Show All Treatment Approach Considerations

  • Antibiotic Therapy Prevention Long-Term Monitoring Show All Guidelines Medication Medication Summary

Antibiotics, Other Show All Questions & Answers Media Gallery References Overview Background Chlamydial infection can cause disease in many organ systems, including the genitourinary tract. Chlamydiae are small gram-negative obligate intracellular microorganisms that preferentially infect squamocolumnar epithelial cells. They include the genera Chlamydia (of which the type species is Chlamydia trachomatis) and Chlamydophila (eg, Chlamydophila pneumoniae and Chlamydophila psittaci).


Age factors in chlamydial genitourinary infection relate to the age of first sexual exposure and the frequency of exposure. Chlamydia is most prevalent in persons aged 15-24 years. Acquisition rates are comparable for the 2 sexes. Women are more likely to be asymptomatic than men (80% vs 50%); however, they are also more likely to develop long-term complications (eg, PID and infertility).


The Center for Genitourinary Reconstruction offers individualized and advanced surgical treatment options for patients with common and uncommon lower urinary tract and genital conditions, disorders and anomalies. Patients primarily consist of male adolescents and adults, but also include some female patients requiring abdominopelvic reconstructive surgery or care for congenital genitourinary system abnormalities as they transition into adolescence and adulthood.


The genitourinary tract is the system most often affected by congenital defects (problems present at the time of birth). However, as children with congenital anomalies of the genitourinary system are entering adolescence and adulthood with excellent health, the issues of sexuality, genital appearance and function, urinary and bowel incontinence, and fertility become important health and quality of life matters. In addition, patients who are born with these problems later experience typical age-related urological problems such as prostate enlargement and prostate cancer that are then more difficult to treat as a result of their previous condition or prior surgeries.


The Department of Pathology offers a one-year position in the Advanced Specialty Training Program (ASTP) in genitourinary pathology. The candidate will be offered a junior faculty position at the rank of instructor (non-tenure eligible) in the Department of Pathology at Northwestern University Feinberg School of Medicine.


Urology of Virginia is an outpatient practice that provides treatment for kidney, urinary tract, prostate, pelvic or other urological needs. Our trainees provide surgical services for disorders of the male and female genitourinary tract at the practice's Devine-Jordan Center for Reconstructive Surgery and Pelvic Health. Faculty train fellows on the clinical aspects of diagnosis, medical and surgical therapy, and the prevention of and reconstruction for these disease processes. As the fellowship progresses, trainees may function as direct supervisors of a senior resident-level physician, who will function as a first-assistant while an attending physician provides overall supervision of advanced procedures. 2ff7e9595c


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